Val-Ala-PAB
Val-Ala-PAB is a cleavable ADC linker that can be used for ADCs synthesis[1].
Product Specifications
CAS Number
[1343476-44-7]
UNSPSC
12352200
Hazard Statement
H302, H315, H319, H335
Target
ADC Linker
Type
Biochemical Assay Reagents
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-ala-pab.html
Purity
99.88
Solubility
DMSO : 116.67 mg/mL (ultrasonic)
Smiles
CC(C)[C@H](N)C(N[C@@H](C)C(NC1=CC=C(C=C1)CO)=O)=O
Molecular Formula
C15H23N3O3
Molecular Weight
293.37
Precautions
H302, H315, H319, H335
References & Citations
[1]Cox N, et al. Integrin-Targeting Knottin Peptide-Drug Conjugates Are Potent Inhibitors of Tumor Cell Proliferation. Angew Chem Int Ed Engl. 2016 Aug 16;55 (34) :9894-7.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Biochemical Assay Reagents
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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