Ceftezole

Ceftezole (CTZ) is a broad-spectrum cephem antibiotic against many species of gram-positive and gram-negative bacteria. Ceftezole (CTZ) is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity[1][2].

Product Specifications

CAS Number

[26973-24-0]

Product Name Alternative

CTZ

UNSPSC

12352005

Hazard Statement

H302+H312+H332-H410

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/ceftezole.html

Solubility

10 mM in DMSO

Smiles

O=C(C(N12)=C(CSC3=NN=CS3)CS[C@]2([H])[C@H](NC(CN4N=NN=C4)=O)C1=O)O

Molecular Formula

C13H12N8O4S3

Molecular Weight

440.48

Precautions

P261-P264-P270-P271-P273-P280-P302+P352-P304+P340-P330-P362+P364-P391-P501

References & Citations

[1]Lee DS, et al. Ceftezole, a cephem antibiotic, is an alpha-glucosidase inhibitor with in vivo anti-diabetic activity. Int J Mol Med. 2007 Sep;20 (3) :379-83.|[2]Harada Y, et al. Ceftezole, a new cephalosporin C derivative II. Distribution and excretion in parenteral administration. J Antibiot (Tokyo) . 1976 Oct;29 (10) :1071-82.