ANK peptide
ANK peptide is a novel peptide designed based on the conserved residues of single ankyrin motif. ANK peptide is a synuclein-γ (SNCG) inhibitor that binds to SNCG and competes with SNCG-BubR1 interaction to enhance the sensitivity of breast cancer cells to antimicrotubule drugs such as nocodazole and paclitaxel. ANK peptide can be used in the study of cancer[1].
Product Specifications
CAS Number
929207-58-9
UNSPSC
12352209
Target
Amino Acid Derivatives
Type
Reference compound
Related Pathways
Others
Field of Research
Cancer
Smiles
NCCCC[C@H](N)C(NCC(N[C@@H](CC(N)=O)C(N[C@@H](CO)C(N[C@@H](C)C(N[C@@H](CC(C)C)C(N[C@H](C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](CO)C(N[C@@H](CCC(N)=O)C(N[C@H](C(NCC(N[C@H](C(N[C@@H](CC(C)C)C(NCC(N[C@@H](CS)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CCC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(NCC(N[C@@H](C)C(N[C@@H](CC(N)=O)C(N[C@@H](C(C)C)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCSC)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(N)=O)C(N[C@H](C(NCC(O)=O)=O)CC1=CN=CN1)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=C(C=C2)O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)CC3=CN=CN3)=O)=O)CC4=CN=CN4)=O)=O)=O)=O)=O)CC5=CN=CN5)=O)=O)=O)=O)=O)=O
Molecular Formula
C152H244N52O46S2
Molecular Weight
3600.01
References & Citations
[1]Singh VK, et al. Synuclein-gamma targeting peptide inhibitor that enhances sensitivity of breast cancer cells to antimicrotubule drugs. Cancer Res. 2007 Jan 15;67 (2) :626-33.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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