JTV-803 (mesylate)
JTV-803 mesylate is a human factor Xa inhibitor with oral anticoagulant activity. JTV-803 exhibits competitive inhibition of human factor Xa, with a Ki value of 0.019μM and IC50Value is 0.081μM. JTV-803 is 100 times more selective at inhibiting human factor Xa than its comparator. JTV-803 is an effective oral anticoagulant for the prevention of thrombosis[1].
Product Specifications
CAS Number
247131-79-9
UNSPSC
12352005
Target
Endogenous Metabolite
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/jtv-803-mesylate.html
Smiles
O=C(C1(CCN(CC1)C2=CC=NC=C2)COC3=CC=C4C(CN(CC4)C(N)=N)=C3)O.O=S(O)(C)=O
Molecular Formula
C23H31N5O6S
Molecular Weight
505.59
References & Citations
[1]Antithrombotic effects of a synthetic inhibitor of activated factor X, JTV-803, in animals
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 1
Frequently Asked Questions
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