Bis-sulfone-PEG4-DBCO
Product Specifications
CAS Number
1854034-70-0
UNSPSC Description
Bis-sulfone-PEG4-DBCO is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Bis-sulfone-PEG4-DBCO is a click chemistry reagent, it contains a DBCO group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
Target Antigen
PROTAC Linkers
Type
Reference compound
Related Pathways
PROTAC
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/bis-sulfone-peg4-dbco.html
Smiles
O=C(C1=CC=C(C(C(CS(=O)(C2=CC=C(C)C=C2)=O)CS(=O)(C3=CC=C(C)C=C3)=O)=O)C=C1)NCCOCCOCCOCCOCCC(NCCC(N4C5=C(C#CC6=C(C4)C=CC=C6)C=CC=C5)=O)=O
Molecular Weight
1006.19
References & Citations
[1]Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-1014.
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