FR-62765
Product Specifications
UNSPSC Description
FR-62765 is a derivative of WF-3681. FR-62765 can significantly inhibit the accumulation of sorbitol in the sciatic nerve and the decrease of motor nerve conduction velocity in the tail of diabetic neuropathy rats, which can be used in the research of diabetic neuropathy[1].
Target Antigen
Aldose Reductase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/fr-62765.html
Smiles
O=C1OC(CCC(OCC)=O)C(C2=CC=CC=C2)=C1OC
Molecular Weight
290.31
References & Citations
[1]Nishikawa M, et al. Studies on WF-3681, a novel aldose reductase inhibitor. IV. Effect of FR-62765, a derivative of WF-3681, on the diabetic neuropathy in rats. J Antibiot (Tokyo). 1991 Apr;44(4):441-4.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-105485/FR-62765-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-105485/
Clinical Information
No Development Reported
CAS Number
105346-34-7
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