β2AR antagonist 1
Product Specifications
UNSPSC Description
β2AR antagonist 1 (Cmpd-15PA) is an antagonist of β2 adrenergic receptor (β2AR). β2AR antagonist 1 binds to the intracellular surface of the β2AR[1].
Target Antigen
Adrenergic Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/β2ar-antagonist-1.html
Smiles
NC(C(C=C1)=CC=C1C[C@@H](C(N[C@H](C(NCCOCCOCCOCC(O)=O)=O)CC2=CC(Br)=CC=C2)=O)NC(C(C3=CC=CC=C3)C4CCCCC4)=O)=O
Molecular Weight
823.77
References & Citations
[1]Liu X, et al. Mechanism of intracellular allosteric β2AR antagonist revealed by X-ray crystal structure. Nature. 2017 Aug 24;548(7668):480-484.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-136960/β2AR-antagonist-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-136960/
Clinical Information
No Development Reported
CAS Number
2135743-21-2
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