ALDH1A1-IN-5
Product Specifications
UNSPSC Description
ALDH1A1-IN-5 (compound 25) is a potent aldehyde dehydrogenase 1A1 (ALDH1A1) inhibitor with EC50 value of 83, 45, 43 µM for ALDH1A1, ALDH1A2, ALDH1A3, respectively. ALDH1A1-IN-5 has the potential for the research of high-grade serous ovarian cancer (HGSOC)[1].
Target Antigen
Aldehyde Dehydrogenase (ALDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/aldh1a1-in-5.html
Solubility
10 mM in DMSO
Smiles
OC1=C(C=CC=C1CNC2=NC3=CC(Cl)=CC=C3N2CC4COC4)Cl
Molecular Weight
378.25
References & Citations
[1]Takahashi C, et al. Development of substituted benzimidazoles as inhibitors of human aldehyde dehydrogenase 1A isoenzymes. Chem Biol Interact. 2024 Mar 1;391:110910.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-158026/ALDH1A1-IN-5-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-158026/
Clinical Information
No Development Reported
Curated Selection
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