Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione

Selected Variant

HY-141555-01

Size: 1 mg

5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC50 of 429 and 467 μM. 5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione inhibits mushroom tyrosinase weakly, with Ki of 1.9 μM[1][2].

Product Specifications

CAS Number

333409-31-7

UNSPSC

12352005

Target

Phosphodiesterase (PDE) ; Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-5-1-3-propanediyl-bis-1-3-4-oxadiazole-2-3h-thione.html

Smiles

S=C1OC(CCCC2=NNC(O2)=S)=NN1

Molecular Formula

C7H8N4O2S2

Molecular Weight

244.29

References & Citations

[1]Khan KM, et al., 1,3,4-Oxadiazole-2 (3H) -thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors. Bioorg Med Chem. 2009 Nov 15;17 (22) :7816-22. |[2]Ghani U, et al., New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2 (3H) -thiones, 1,3,4-oxadiazole-2 (3H) -thiones, 4-amino-1,2,4-triazole-5 (4H) -thiones, and substituted hydrazides to the dicopper active site. Bioorg Med Chem. 2010 Jun 1;18 (11) :4042-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Price

Sign In for Pricing

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog