Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione

5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione is a weak inhibitor for snake venom and human recombinant phosphodiesterase 1 with IC50 of 429 and 467 μM. 5,5′- (1,3-Propanediyl) bis-1,3,4-oxadiazole-2 (3H) -thione inhibits mushroom tyrosinase weakly, with Ki of 1.9 μM[1][2].

Product Specifications

CAS Number

333409-31-7

UNSPSC

12352005

Target

Phosphodiesterase (PDE) ; Tyrosinase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/5-5-1-3-propanediyl-bis-1-3-4-oxadiazole-2-3h-thione.html

Smiles

S=C1OC(CCCC2=NNC(O2)=S)=NN1

Molecular Formula

C7H8N4O2S2

Molecular Weight

244.29

References & Citations

[1]Khan KM, et al., 1,3,4-Oxadiazole-2 (3H) -thione and its analogues: a new class of non-competitive nucleotide pyrophosphatases/phosphodiesterases 1 inhibitors. Bioorg Med Chem. 2009 Nov 15;17 (22) :7816-22. |[2]Ghani U, et al., New potent inhibitors of tyrosinase: novel clues to binding of 1,3,4-thiadiazole-2 (3H) -thiones, 1,3,4-oxadiazole-2 (3H) -thiones, 4-amino-1,2,4-triazole-5 (4H) -thiones, and substituted hydrazides to the dicopper active site. Bioorg Med Chem. 2010 Jun 1;18 (11) :4042-8.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL
BNC470391-500 1x 500 µL

CD81 / TAPA-1 (1.3.3.22), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
CD45RO (190-2F2.5), CF640R conjugate, 0.1mg/mL
BNC401081-100 1x 100 µL

CD45RO (190-2F2.5), CF640R conjugate, 0.1mg/mL

Sign In for Pricing
View Details
MyoD1 (MYD712), CF647 conjugate, 0.1mg/mL
BNC470712-500 1x 500 µL

MyoD1 (MYD712), CF647 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
Glypican-3 (1G12), CF594 conjugate, 0.1mg/mL
BNC940862-500 1x 500 µL

Glypican-3 (1G12), CF594 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
BOB.1 (B-Cell Marker) (BOB1/2424), CF568 conjugate, 0.1mg/mL
BNC682424-100 1x 100 µL

BOB.1 (B-Cell Marker) (BOB1/2424), CF568 conjugate, 0.1mg/mL

Sign In for Pricing
View Details
SOX9 / SRY-box 9 (SOX9/2398), CF488A conjugate, 0.1mg/mL
BNC882398-100 1x 100 µL

SOX9 / SRY-box 9 (SOX9/2398), CF488A conjugate, 0.1mg/mL

Sign In for Pricing
View Details