HU 433

HU 433 is a synthetic cannabinoid CB2 receptor agonist and is the enantiomer of HU 308 (HY-161510) . HU 433 exerts its anti-inflammatory and neuroprotective effects by binding to CB2 receptors. HU 433 can be used in the study of neuroinflammation and retinal diseases[1].

Product Specifications

CAS Number

[1220887-84-2]

UNSPSC

12352005

Target

Cannabinoid Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease; Others

Assay Protocol

https://www.medchemexpress.com/hu-433.html

Smiles

COC1=C(C(OC)=CC(C(C)(CCCCCC)C)=C1)[C@@H]2C=C([C@@H]3C[C@H]2C3(C)C)CO

Molecular Formula

C27H42O3

Molecular Weight

414.62

References & Citations

[1]Young A P, et al. Enantiomeric Agonists of the Type 2 Cannabinoid Receptor Reduce Retinal Damage during Proliferative Vitreoretinopathy and Inhibit Hyperactive Microglia In Vitro[J]. ACS Pharmacology & Translational Science, 2024.