R162
R162 is a potent inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1), with anti-cancer properties.
Product Specifications
CAS Number
64302-87-0
UNSPSC
12352005
Hazard Statement
H302, H312, H332
Target
Glutamate Dehydrogenase (GLDH)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/R162.html
Purity
99.98
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C) |Ethanol : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C2=C(C=CC=C2)C(C3=CC=C(CC=C)C(O)=C13)=O
Molecular Formula
C17H12O3
Molecular Weight
264.28
Precautions
H302, H312, H332
References & Citations
[1]Jin L, et al. Glutamate dehydrogenase 1 signals through antioxidant glutathione peroxidase 1 to regulate redox homeostasis and tumor growth. Cancer Cell. 2015 Feb 9;27 (2) :257-70.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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