Ro 09-1679
Ro 09-1679 is a thrombin inhibitor, with an IC50 of 33.6 μM. Ro 09-1679 inhibits the enzyme activities, with IC50 values of 3.3, 0.04 and 0.0346 μM for factor Xa, trypsin and papain, respectively[1].
Product Specifications
CAS Number
141426-89-3
UNSPSC
12352211
Target
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ro-09-1679.html
Smiles
NC(NCCC[C@@H](C(N[C@@H](CC(C)C)C(N[C@H](C=O)CCCNC(N)=N)=O)=O)NC(/C=C/C(O)=O)=O)=N
Molecular Formula
C22H39N9O6
Molecular Weight
525.60
References & Citations
[1]Kamiyama T, et al. Ro 09-1679, a novel thrombin inhibitor. J Antibiot (Tokyo) . 1992 Mar;45 (3) :424-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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