Topilutamide

Topilutamide is a topical nonsteroidal antiandrogen (NSAA) .

Product Specifications

CAS Number

[260980-89-0]

Product Name Alternative

BP766; Fluridil

UNSPSC

12352005

Hazard Statement

H319, H411

Target

Androgen Receptor

Type

Reference compound

Related Pathways

Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Topilutamide.html

Concentration

10mM

Purity

99.91

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC=C([N+]([O-])=O)C(C(F)(F)F)=C1)C(C)(O)CNC(C(F)(F)F)=O

Molecular Formula

C13H11F6N3O5

Molecular Weight

403.23

Precautions

H319, H411

References & Citations

[1]Suresh PS, et al. Review of HPLC and LC-MS/MS assays for the determination of various nonsteroidal anti-androgens used in the treatment of prostate cancer. Biomed Chromatogr. 2017 Jun 21.|[2]Sovak M, Seligson AL, Kucerova R, Bienova M, Hajduch M, Bucek M. Fluridil, a rationally designed topical agent for androgenetic alopecia: first clinical experience [published correction appears in Dermatol Surg 2002 Oct;28 (8) :following 970]. Dermatol Surg. 2002;28 (8) :678-685.