SJH1-62B
SJH1-62B is a proteolysis targeting chimera (PROTAC) that can target the androgen receptor (AR) [1].
Product Specifications
UNSPSC
12352005
Target
PROTACs
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/sjh1-62b.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=NN=C(N2CCN(CCCCCCCNC(CCCOC3=CC=CC(CC4CCN(C(C=C)=O)CC4)=C3)=O)CC2)C=C1)NC5CCC(OC6=CC=C(C#N)C(Cl)=C6)CC5
Molecular Formula
C48H63ClN8O5
Molecular Weight
867.52
References & Citations
[1]Hong SH, et al. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation. ACS Chem Biol. 2024 Feb 16;19 (2) :442-450.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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