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SJH1-62B

SJH1-62B is a proteolysis targeting chimera (PROTAC) that can target the androgen receptor (AR) [1].

Product Specifications

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/sjh1-62b.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=NN=C(N2CCN(CCCCCCCNC(CCCOC3=CC=CC(CC4CCN(C(C=C)=O)CC4)=C3)=O)CC2)C=C1)NC5CCC(OC6=CC=C(C#N)C(Cl)=C6)CC5

Molecular Formula

C48H63ClN8O5

Molecular Weight

867.52

References & Citations

[1]Hong SH, et al. Exploiting the Cullin E3 Ligase Adaptor Protein SKP1 for Targeted Protein Degradation. ACS Chem Biol. 2024 Feb 16;19 (2) :442-450.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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