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Sodium α-ketoisocaproate

Selected Variant

HY-W017387-01

Size: 100 mg

Sodium α-ketoisocaproate, the transamination product of leucine, stimulates insulin secretion. Sodium α-ketoisocaproate (α-KIC) can either be oxidized to acetyl-CoA and acetoacetate, or it yields leucine through transamination with glutamate, forming α-KG.

Product Specifications

CAS Number

4502-00-5

Product Name Alternative

Sodium 4-methyl-2-oxopentanoate; 2-Ketoisocaproic acid (sodium salt)

UNSPSC

12352300

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/sodium-α-ketoisocaproate.html

Purity

99.05

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

[Na].O=C(O)C(=O)CC(C)C

Molecular Formula

C6H9NaO3

Molecular Weight

152.12

Precautions

H302, H315, H319, H335

References & Citations

[1]Mary E Rabaglia, et al. Alpha-Ketoisocaproate-induced hypersecretion of insulin by islets from diabetes-susceptible mice. Am J Physiol Endocrinol Metab. 2005 Aug;289 (2) :E218-24.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Human Endogenous Metabolite

Available Sizes

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