N6-Methyladenosine 5'-monophosphate (disodium salt)

N6-Methyladenosine 5'-monophosphate disodium salt is an activator of glycogen phosphorylase b, with a Ka value of 22 µM[1]. N6-Methyladenosine 5'-monophosphate disodium salt is a non-competitive rat adenylate kinase II inhibitor[2].

Product Specifications

CAS Number

[81921-35-9]

UNSPSC

12352005

Target

Phosphorylase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-sugar/lipid metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/n6-methyladenosine-5-monophosphate-disodium-salt.html

Concentration

10mM

Purity

99.84

Solubility

H2O : 25 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

CNC1=C2C(N([C@H]3[C@H](O)[C@H](O)[C@@H](COP(O[Na])(O[Na])=O)O3)C=N2)=NC=N1

Molecular Formula

C11H14N5Na2O7P

Molecular Weight

405.21

References & Citations

[1]Groner Y, et al. 5'-Capping structures of Artemia salina mRNA and the translational inhibition by cap analogs. Eur J Biochem. 1976 Dec;71 (1) :281-93.|[2]Hai TT, et al. Species- or isozyme-specific enzyme inhibitors. 9. Selective effects in inhibitions of rat pyruvate kinase isozymes by adenosine 5'-diphosphate derivatives. J Med Chem. 1982 Oct;25 (10) :1184-8.