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TEAD ligand 1

TEAD ligand 1 is the ligand for target protein TEAD. TEAD ligand 1 is utilized for synthesis of PROTAC TEAD degrader-1.

Product Specifications

CAS Number

2971850-47-0

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; YAP

Type

Reference compound

Related Pathways

PROTAC; Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tead-ligand-1.html

Solubility

10 mM in DMSO

Smiles

O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC(Br)=CC=C4)C

Molecular Formula

C25H18BrF3N2O

Molecular Weight

499.32

References & Citations

[1]Li H, et al., Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders. ACS Med Chem Lett. 2024 Apr 22;15 (5) :631-639.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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