TEAD ligand 1
TEAD ligand 1 is the ligand for target protein TEAD. TEAD ligand 1 is utilized for synthesis of PROTAC TEAD degrader-1.
Product Specifications
CAS Number
2971850-47-0
UNSPSC
12352005
Target
Ligands for Target Protein for PROTAC; YAP
Type
Reference compound
Related Pathways
PROTAC; Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/tead-ligand-1.html
Solubility
10 mM in DMSO
Smiles
O=C(C1=CC=C2C(C3=CC=C(C(F)(F)F)C=C3)=CC=CC2=C1)N[C@H](C4=NC(Br)=CC=C4)C
Molecular Formula
C25H18BrF3N2O
Molecular Weight
499.32
References & Citations
[1]Li H, et al., Design, Synthesis, and Bioevaluation of Transcriptional Enhanced Assocciated Domain (TEAD) PROTAC Degraders. ACS Med Chem Lett. 2024 Apr 22;15 (5) :631-639.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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