Antiparasitic agent-22
Antiparasitic agent-22 (Compound 24) is a pan antiparasitic agent, that inhibits T. Brucei, L. infantum, L. tropica promastigotes (IC50 of 2.41, 5.95, 8.98 μM), L. infantum amastigotes (IC50 of 8.18 μM) and P. falciparum W2 strain (IC50 of 0.155 μM) . Antiparasitic agent-22 exhibits low cytotoxicity against THP1, with CC50 of 64.16 μM[1].
Product Specifications
CAS Number
9007-83-4
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/antiparasitic-agent-22.html
Solubility
10 mM in DMSO
Smiles
BrC1=NOC(C2=NN=C(C3=CC=C(OCC4CCCCC4)C=C3)O2)C1
Molecular Formula
C18H20BrN3O3
Molecular Weight
406.27
References & Citations
[1]Corfu AI, et al., Discovery of 1,3,4-Oxadiazole Derivatives as Broad-Spectrum Antiparasitic Agents. ACS Infect Dis. 2024 May 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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