H-ILE-ARG-VAL-VAL-MET-OH

H-ILE-ARG-VAL-VAL-MET-OH is a pentapeptide from C7 with a domain that supports cell attachment. H-ILE-ARG-VAL-VAL-MET-OH is also the sequence fragment that binds to the thrombospondin-1 (TS1) receptor[1][2].

Product Specifications

CAS Number

[149234-05-9]

UNSPSC

12352209

Target

TGF-β Receptor

Type

Peptides

Related Pathways

TGF-beta/Smad

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/h-ile-arg-val-val-met-oh.html

Solubility

10 mM in DMSO

Smiles

CSCC[C@@H](C(O)=O)NC([C@H](C(C)C)NC([C@H](C(C)C)NC([C@H](CCCNC(N)=N)NC([C@@H](N)[C@@H](C)CC)=O)=O)=O)=O

Molecular Formula

C27H52N8O6S

Molecular Weight

616.82

References & Citations

[1]Kosfeld MD, et al. Identification of a new cell adhesion motif in two homologous peptides from the COOH-terminal cell binding domain of human thrombospondin. J Biol Chem. 1993 Apr 25;268 (12) :8808-14. |[2]Frazier, et al. Thrombospondin 1 subfragments that bind to thrombospondin 1 receptor and inhibit cell adhesion: United States, US5399667[P]. 1995-03-21.