CD73-IN-4
CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor, with an IC50 of 2.6 nM for human CD73. CD73-IN-4 is potential for the research of cancer immunology[1].
Product Specifications
CAS Number
2216764-29-1
UNSPSC
12352005
Target
CD73
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cd73-in-4.html
Concentration
10mM
Purity
99.21
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
ClC1=NC(N([C@@H]([C@H](O)[C@@H]2O)O[C@@H]2COCP(O)(O)=O)N=C3)=C3C(NC4CCCC4)=N1
Molecular Formula
C16H23ClN5O7P
Molecular Weight
463.81
References & Citations
[1]Ehesan U Sharif , et al. Discovery of Potent and Selective Methylenephosphonic Acid CD73 Inhibitors. J Med Chem. 2021 Jan 5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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