Kocurin
Product Specifications
UNSPSC Description
Kocurin (PM181104) is a thiazolyl cyclic-peptide antibiotic. Kocurin inhibits bacterial growth by impeding bacterial protein biosynthesis during the translation phase. Kocurin has strong inhibitory activity against gram-positive bacteria, but no activity against fungi and Gram-negative bacteria[1].
Target Antigen
Antibiotic; Bacterial
Type
Peptides
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/kocurin.html
Smiles
CC(OC(C1=CC=C(C2=NC(C(NC(C(N[C@@H](C)C(N3[C@@H](CCC3)C(NC(C(NC(C(N)=O)=C)=O)=C)=O)=O)=O)=C)=O)=CS2)N=C1C4=CSC(C5=CSC([C@@]6([H])N(CCC6)C([C@@H](NC([C@@]7([H])N=C(SC7)[C@@H](NC(C8=CSC([C@@H](N9)CC(N)=O)=N8)=O)CC%10=CC=CC=C%10)=O)CC%11=CC=C(C=C%11)O)=O)=N5)=N4)=N%12)=C%12C9=O
Molecular Weight
1515.70
References & Citations
[1]Mahajan G, et al. In vitro and in vivo activities of antibiotic PM181104. Antimicrob Agents Chemother. 2013 Nov;57(11):5315-9.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-W748000/Kocurin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-W748000/
Clinical Information
No Development Reported
CAS Number
1374772-61-8
Curated Selection
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