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2'-RIBOTAC-U recruiter-linker

2'-RIBOTAC-U recruiter-linker (Compound 9) consists of RNase L recruiter and linker. 2'-RIBOTAC-U recruiter-linker is reacted separately with 2’-azido-uridine or 5’-azidomethyl-uridine via copper-catalyzed click chemistry, resulting in the formation of 2’-RIBOTAC-U and 5’-RIBOTAC-U, respectively. 2’-RIBOTAC-U has anti-SARS-CoV-2 activity[1].

Product Specifications

UNSPSC

12352005

Target

Biochemical Assay Reagents

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/2-ribotac-u-recruiter-linker.html

Solubility

10 mM in DMSO

Smiles

OC1=CC(/C=C2SC(NC3=CC=CC=C3)=C(C(OCC)=O)C\2=O)=CC=C1OCCOCCOCCOCCNC(CCC#C)=O

Molecular Formula

C33H38N2O9S

Molecular Weight

638.73

References & Citations

[1]Min Y, et al. Developing nucleoside tailoring strategies against SARS-CoV-2 via ribonuclease targeting chimera. Sci Adv. 2024 Apr 12;10 (15) :eadl4393.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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