Val-Cit-PAB-DEA-Dxd
Val-Cit-PAB-DEA-Dxd (compound 81) is a Drug-Linker Conjugates for ADC, which is composed of a linker and a toxic molecule Dxd (DNA topoisomerase I inhibitor) . Val-Cit-PAB-DEA-Dxd can be used for ADC synthesis[1].
Product Specifications
CAS Number
2964543-53-9
UNSPSC
12352203
Target
Drug-Linker Conjugates for ADC
Type
Reference compound
Related Pathways
Antibody-drug Conjugate/ADC Related
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/val-cit-pab-dea-dxd.html
Solubility
10 mM in DMSO
Smiles
CC(C)[C@H](N)C(N[C@@H](CCCNC(N)=O)C(NC(C=C1)=CC=C1COC(N(C)CCN(C)C(OCC(N[C@@H]2C3=C4C(C(N5C4)=CC([C@](O)(C(OC6)=O)CC)=C6C5=O)=NC7=CC(F)=C(C)C(CC2)=C73)=O)=O)=O)=O)=O
Molecular Formula
C50H61FN10O12
Molecular Weight
1013.08
References & Citations
[1]Dechun Wu, et al. Pegylated antibody hydroxyl-bearing drug conjugate. Patent WO2023151679A1.
Shipping Conditions
Room temperature
Scientific Category
ADC Related
Clinical Information
No Development Reported
Frequently Asked Questions
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