T3SS-IN-4
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice[1].
Product Specifications
CAS Number
2316760-41-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t3ss-in-4.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C(F)C=CC=C2C=C3C1=NC4=C3C=CC=C4
Molecular Formula
C16H11FN2
Molecular Weight
250.27
References & Citations
[1]Shao J, et al. Application and Mechanism of Cryptolepine and Neocryptolepine Derivatives as T3SS Inhibitors for Control of Bacterial Leaf Blight on Rice. J Agric Food Chem. 2024;72 (13) :6988-6997.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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