T3SS-IN-4
T3SS-IN-4 (Compound Z-8) is a T3SS inhibitor that can inhibit the expression of Xanthomonas oryzae pv oryzae (Xoo) T3SS-related genes without affecting bacterial growth. T3SS-IN-4 can effectively reduce the hypersensitive response (HR) induced by Xoo in tobacco and lower the pathogenicity of Xoo in rice[1].
Product Specifications
CAS Number
2316760-41-3
UNSPSC
12352005
Target
Bacterial
Type
Reference compound
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/t3ss-in-4.html
Solubility
10 mM in DMSO
Smiles
CN1C2=C(F)C=CC=C2C=C3C1=NC4=C3C=CC=C4
Molecular Formula
C16H11FN2
Molecular Weight
250.27
References & Citations
[1]Shao J, et al. Application and Mechanism of Cryptolepine and Neocryptolepine Derivatives as T3SS Inhibitors for Control of Bacterial Leaf Blight on Rice. J Agric Food Chem. 2024;72 (13) :6988-6997.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
IRBAMLSMYD2AP990120UL 120 µL
Rabbit Anti SMYD2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 50% glycerol, pH7.3) (Immunofluorescence) 120ul
Sign In for Pricing
View Details 
MBS6450880-01 0.1 mL
EXTL2 (Exostoses (Multiple)-like 2, EXTR2) (MaxLight 750)
Sign In for Pricing
View Details MBS6450880-02 5x 0.1 mL
EXTL2 (Exostoses (Multiple)-like 2, EXTR2) (MaxLight 750)
Sign In for Pricing
View Details