Melanoma Marker (MART-1 + Tyrosinase + gp100) (DT101+ BC199 + T311 + HMB45), Biotin conjugate, 0.1mg/mL
Selected Variant
BNCB0704-500
Size: 1x 500 µL
This antibody cocktail recognizes three melanoma-specific proteins, which include MART-1, Tyrosinase and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Tyrosinase is one of the targets for cytotoxic T-cell recognition in melanoma patients. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. This cocktail of three markers is designed for extremely sensitive labeling of formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.
Product Specifications
CAS Number
9007-83-4
Synonyms
Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; PMEL17
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene ID
2315; 6490
Host
Mouse
Species Reactivity
Human
Reactivity
Melanoma cells
Immunogen
Target Antigen
Melanoma cells
Clonality
Monoclonal
Clone
DT101 BC199 T311 HMB45
Type
Primary
Source
Animal
Origin
Animal
Applications
IHC, FFPE (verified)
Field of Research
Cancer
Positive Control
SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues.
Stability
2 years
Concentration
0.1 mg/mL
Buffer
PBS, 0.1% BSA, 0.05% azide
Molecular Weight
20-22 kDa (doublet) (MART-1) ; 90-100 kDa (gp100) ; 70-80 kDa (Tyrosinase)
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG2a, kappa
Species
Mus musculus (mouse), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.
Classification
0.05% sodium azide (CAS 26628-22-8)
Conjugate
Biotin
Price
Documents
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