3-Indoleacetonitrile
3-Indoleacetonitrile is an indole derivative with anti-influenza activity. 3-Indoleacetonitrile is a plant hormone produced by cruxiferous vegetables. 3-Indoleacetonitrile exerts profound antiviral activity against a broad spectrum of influenza A viruses, HSV-1 and VSV viruses in vitro. 3-Indoleacetonitrile diminishes lung virus titers and alleviates lung lesions in vivo. 3-Indoleacetonitrile induces an increase in mitochondrial antiviral-signaling (MAVS) protein levels. 3-Indoleacetonitrile can be used in research for combating viral infections including COVID-19, HSV-1, and VSV[1][2].
Product Specifications
CAS Number
771-51-7
UNSPSC
12352005
Hazard Statement
H301, H311, H331
Target
Endogenous Metabolite; HSV; Influenza Virus; VSV
Type
Natural Products
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/3-indoleacetonitrile.html
Purity
99.93
Solubility
DMSO : 100 mg/mL|H2O : 1 mg/mL (ultrasonic)
Smiles
N#CCC1=CNC2=C1C=CC=C2
Molecular Formula
C10H8N2
Molecular Weight
156.19
Precautions
H301, H311, H331
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
Human Endogenous Metabolite
Available Sizes
Frequently Asked Questions
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