Melanoma Marker (MART-1 + gp100) (DT101+ BC199 + HMB45), 1mg/mL

This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Product Specifications

CAS Number

9007-83-4

Synonyms

Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A; PMEL17

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene Name

MLANA; SILV

Gene ID

2315; 6490

NCBI Gene ID

154069 ; 95972

UniProt

Q16655; P40967

Swiss Prot

Q16655 ; P40967

Host

Mouse

Species Reactivity

Human

Reactivity

Melanoma cells

Immunogen

Recombinant hMART-1 protein (DT101 & BC199) ; Extract of pigmented melanoma metastases from lymph nodes (HMB45)

Target Antigen

Melanoma cells

Clonality

Monoclonal

Clone

DT101 BC199 HMB45

Type

Primary

Source

Animal

Origin

Animal

Applications

IHC, FFPE (verified)

Field of Research

Cancer

Positive Control

SK-MEL-13 and SK-MEL-19 melanoma cell lines. Human melanoma tissues.

Stability

2 years

Concentration

1 mg/mL

Buffer

PBS, no BSA, no azide

Molecular Weight

20-22 kDa (doublet) (MART-1) ; 90-100 kDa (gp100)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Mus musculus (mouse)

Classification

PBS, no BSA, no sodium azide (CAS 26628-22-8)

Conjugate

Purified, BSA-free

Documents

Product Datasheet

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