Barbinervic acid
Barbinervic acid is a glutaminase inhibitor with an IC50 of 14 μM. Barbinervic acid can be used for the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
64199-78-6
UNSPSC
12352211
Target
Glutaminase
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/barbinervic-acid.html
Solubility
10 mM in DMSO
Smiles
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@](C)([C@@H](CC4)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
Molecular Formula
C30H48O5
Molecular Weight
488.70
References & Citations
[1]Atsumi Shimada, et al. Pentacyclic triterpene acids, rotungenic acid and barbinervic acid, from fresh leaves of Diospyros kaki Thunberg and their glutaminase inhibitory activities. Nat Prod Res. 2022 Nov 26;1-5.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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