Triciribine phosphate-d3
Triciribine phosphate-d3 (TCN-P-d3) is a deuterated compound of Triciribine phosphate (TCN-P) . TCN-P inhibits adenosine monophosphate (AMP) -activated protein kinase through an allosteric mechanism, affecting the first key step in de novo purine biosynthesis. Triciribine phosphate also inhibits inosine monophosphate dehydrogenase, which is the first key step in guanosine nucleotide synthesis. Triciribine phosphate does not affect ligase activity [1].
Product Specifications
Product Name Alternative
TCN-P-d3
UNSPSC
12352005
Target
ATP Synthase; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Metabolic Disease
Purity
99.68
Smiles
NC1=NN(C2=C3C1=CN(C3=NC=N2)[C@@H]4O[C@@H](COP(O)(O)=O)[C@H](O)[C@@H]4O)C([2H])([2H])[2H]
Molecular Formula
C13H14D3N6O7P
Molecular Weight
403.30
References & Citations
[1]E C Moore, Inhibition of two enzymes in de novo purine nucleotide synthesis by triciribine phosphate (TCN-P) . Biochem Pharmacol. 1989, 38, 22.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Frequently Asked Questions
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