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PSMA-BCH

PSMA-BCH (NOTA-PSMA) is a NOTA-conjugated precursor. NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools[1].

Product Specifications

CAS Number

[1703768-73-3]

Product Name Alternative

NOTA-PSMA

UNSPSC

12352005

Target

Radionuclide-Drug Conjugates (RDCs)

Type

Reference compound

Related Pathways

Antibody-drug Conjugate/ADC Related

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/psma-bch.html

Purity

99.93

Solubility

DMSO : 125 mg/mL (ultrasonic) |H2O : 5 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=C([C@@H]1CC[C@H](CC1)CNC(CN2CCN(CCN(CC2)CC(O)=O)CC(O)=O)=O)N[C@H](C(NCCCC[C@@H](C(O)=O)NC(N[C@H](C(O)=O)CCC(O)=O)=O)=O)CC3=CC4=C(C=CC=C4)C=C3

Molecular Formula

C45H64N8O14

Molecular Weight

941.03

References & Citations

[1]Teli Liu, et al. Synthesis and preclinical evaluation of 68Ga-PSMA-BCH for prostate cancer imaging. Bioorg Med Chem Lett. 2019 Apr 1;29 (7) :933-937.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RDC Bifunctional Chelator

Available Sizes

Curated Selection

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