AASS-IN-1
AASS-IN-1 (Compound S-105) is an AASS (2-aminoadipic semialdehyde synthase) inhibitor with an IC50 value of 142 μM. AASS-IN-1 inhibits AASS activity by binding to the LOR domain of AASS. AASS-IN-1 holds potential for research in the field of hyperlysinemia[1].
Product Specifications
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/aass-in-1.html
Purity
98.40
Solubility
DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)
Smiles
O=C1NC2=C(CC1)C=C(C=C2)C(N3[C@@H](CCC3)CN)=O.Cl
Molecular Formula
C15H20ClN3O2
Molecular Weight
309.79
References & Citations
[1]Leandro J, et al. Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biol. 2022 Sep;12 (9) :220179.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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