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AASS-IN-1

AASS-IN-1 (Compound S-105) is an AASS (2-aminoadipic semialdehyde synthase) inhibitor with an IC50 value of 142 μM. AASS-IN-1 inhibits AASS activity by binding to the LOR domain of AASS. AASS-IN-1 holds potential for research in the field of hyperlysinemia[1].

Product Specifications

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/aass-in-1.html

Purity

98.40

Solubility

DMSO : 100 mg/mL (ultrasonic) |H2O : 100 mg/mL (ultrasonic)

Smiles

O=C1NC2=C(CC1)C=C(C=C2)C(N3[C@@H](CCC3)CN)=O.Cl

Molecular Formula

C15H20ClN3O2

Molecular Weight

309.79

References & Citations

[1]Leandro J, et al. Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1. Open Biol. 2022 Sep;12 (9) :220179.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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