N-Cyclopropyl methyl bimatoprost

N-Cyclopropyl methyl bimatoprost (17-Phenyl trinor prostaglandin F2α cyclopropyl methyl amide) is an analog of Bimatoprost (HY-12956) . N-Cyclopropyl methyl bimatoprost is an agonist for Prostaglandin F2α Receptor (FP receptor) . N-Cyclopropyl methyl bimatoprost is potent to reduce the intraocular pressure and attenuate the glaucoma[1][2].

Product Specifications

CAS Number

[1138395-10-4]

Product Name Alternative

17-Phenyl trinor prostaglandin F2α cyclopropyl methyl amide

UNSPSC

12352005

Hazard Statement

H302-H360

Target

Prostaglandin Receptor

Type

Reference compound

Related Pathways

GPCR/G Protein

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/n-cyclopropyl-methyl-bimatoprost.html

Smiles

O[C@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(NCC2CC2)=O)O)O)CCC3=CC=CC=C3

Molecular Formula

C27H39NO4

Molecular Weight

441.60

Precautions

P264-P270-P280-P330-P405-P501

References & Citations

[1]Balapure AK, et al., Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38 (14) :2375-81. |[2]Woodward DF, et al., Pharmacological characterization of a novel antiglaucoma agent, Bimatoprost (AGN 192024) . J Pharmacol Exp Ther. 2003 May;305 (2) :772-85.