Tebuquine
Tebuquine (WR228258), a 4-aminoquinoline, is a potent antimalarial agent. Tebuquine is active against the Chloroquine sensitive HB3 strain and the Chloroquine resistant K1 strain of Plasmodium falciparum with IC50s of 0.9 nM and 20.8 nM, respectively[1].
Product Specifications
CAS Number
74129-03-6
Product Name Alternative
WR228258
UNSPSC
12352005
Target
Parasite
Type
Reference compound
Related Pathways
Anti-infection
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/tebuquine.html
Smiles
ClC1=CC=C(C2=CC(NC3=C4C=CC(Cl)=CC4=NC=C3)=CC(CNC(C)(C)C)=C2O)C=C1
Molecular Formula
C26H25Cl2N3O
Molecular Weight
466.40
References & Citations
[1]P M O'Neill, et al. Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues. J Med Chem. 1997 Feb 14;40 (4) :437-48.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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