VH032-PEG2-NH-BOC
VH032-PEG2-NH-BOC is a Boc-modified VH032 that serves as a ligand for VHL and recruits von Hippel-Lindau (VHL) proteins. VH032-PEG2-NH-BOC will remove the protecting group under acidic conditions and be directly used for PROTAC molecule synthesis. VH032-PEG2-NH-BOC is a key intermediate in the synthesis of PROTAC based on VHL ligand.
Product Specifications
CAS Number
2162120-75-2
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/vh032-peg2-nh-boc.html
Solubility
10 mM in DMSO
Smiles
O=C(NCC1=CC=C(C2=C(C)N=CS2)C=C1)[C@H]3N(C([C@H](C(C)(C)C)NC(COCCOCCNC(OC(C)(C)C)=O)=O)=O)C[C@H](O)C3
Molecular Formula
C33H49N5O8S
Molecular Weight
675.84
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Recombinant Human PPP1CC Protein, His, E.coli-50ug
Glucose 6 phosphate isomerase Recombinant Antibody, PE-Cy7 Conjugated
Anti-DCHS2 Antibody Picoband® FITC Conjugated
