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Rosabulin

Product Specifications

UNSPSC Description

Rosabulin (STA 5312) is a potent and orally active microtubule inhibitor that inhibits microtubule assembly. Rosabulin has broad-spectrum anti-tumor activity[1].

Target Antigen

Microtubule/Tubulin

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Rosabulin.html

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

O=C(NC1=CC(C)=NS1)C(C2=C3C=CC=CN3C(CC4=CC=C(C#N)C=C4)=C2)=O

Molecular Weight

400.45

References & Citations

[1]Keizo Koya,et al. STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers. Cancer Res, Volume 45, 2004.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-14934/Rosabulin-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-14934/Rosabulin-SDS-MedChemExpress.pdf

Clinical Information

Phase 1

CAS Number

501948-05-6

Available Sizes

Curated Selection

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