Rosabulin
Product Specifications
UNSPSC Description
Rosabulin (STA 5312) is a potent and orally active microtubule inhibitor that inhibits microtubule assembly. Rosabulin has broad-spectrum anti-tumor activity[1].
Target Antigen
Microtubule/Tubulin
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Rosabulin.html
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(NC1=CC(C)=NS1)C(C2=C3C=CC=CN3C(CC4=CC=C(C#N)C=C4)=C2)=O
Molecular Weight
400.45
References & Citations
[1]Keizo Koya,et al. STA-5312, a novel tubulin inhibitor, demonstrates the anti-cancer activity against chemotherapy-resistant cancers. Cancer Res, Volume 45, 2004.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-14934/Rosabulin-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-14934/Rosabulin-SDS-MedChemExpress.pdf
Clinical Information
Phase 1
CAS Number
501948-05-6
Available Sizes
Curated Selection
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