Interferon alpha-1 (IFNA1) (2-48), 1mg/mL
This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1) . Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Product Specifications
CAS Number
9007-83-4
Synonyms
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IFNA1
Gene ID
3439
NCBI Gene ID
37026 & 533471
UniProt
P01562
Swiss Prot
P01562
Host
Mouse
Species Reactivity
Human
Reactivity
Interferon Alpha-1
Immunogen
Purified recombinant human IFN-alpha1
Target Antigen
Interferon Alpha-1
Clonality
Monoclonal
Clone
17564
Type
Primary
Source
Animal
Origin
Animal
Field of Research
Cytokines, Immunology, Inflammation
Positive Control
Stimulated human peripheral blood mononuclear cells
Stability
2 years
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
16-27 kDa
Shipping Conditions
RT (ND)
Storage Conditions
Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
Guaranteed for at least 24 months from date of receipt when stored as recommended
Fragment
IgG1, kappa
Species
Mus musculus (mouse)
Classification
PBS, no BSA, no sodium azide (CAS 26628-22-8)
Conjugate
Purified, BSA-free
Documents
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