Lepidiline A
Lepidiline A exhibits cytotoxic activity against HL-60 cells with an IC50 value of 32.3 μM. Lepidiline A targets HSD17B1 activity, increases the bioconversion efficiency of sex hormones (including the conversion of estrogen into 17β-estradiol and 4-androsten-3,7-dione into testosterone), thereby improving the reproductive capacity of fruit flies.[1][2].
Product Specifications
CAS Number
[596093-98-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
17β-HSD
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/lepidiline-a.html
Concentration
10mM
Purity
99.54
Solubility
DMSO : 62.5 mg/mL (ultrasonic)
Smiles
CC1=C(C)[N+](CC2=CC=CC=C2)=CN1CC3=CC=CC=C3.[Cl-]
Molecular Formula
C19H21ClN2
Molecular Weight
312.84
Precautions
H302, H315, H319
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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