Mephenesin
Mephenesin is an NMDA receptor antagonist. Mephenesin is also a central muscle relaxant with antianxiety, muscle-paralyzing and anticonvulsant effects. Mephenesin acts directly on the skeletal muscle fibres to produce skeletal muscle relaxation. Mephenesin is promising for research of spasticity or painful muscle spasm[1][2][3][4][5].
Product Specifications
CAS Number
59-47-2
UNSPSC
12352005
Hazard Statement
H302
Target
IGluR
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Mephenesin.html
Purity
99.69
Solubility
DMSO : ≥ 100 mg/mL
Smiles
OCC(O)COC1=CC=CC=C1C
Molecular Formula
C10H14O3
Molecular Weight
182.22
Precautions
H302
References & Citations
[1]Mephenesin: abuse and dependence. Prescrire Int. 2013 May;22 (138) :127-128.|[2]?cija P, et al. Conformational flexibility of mephenesin. J Phys Chem B. 2014 May 22;118 (20) :5357-5364.|[3]Crankshaw DP, et al. Mephenesin, methocarbamol, chlordiazepoxide and diazepam: actions on spinal reflexes and ventral root potentials. Br J Pharmacol. 1970 Jan;38 (1) :148-56.|[4]Ludwig B J, et al. Muscle-paralyzing compounds related to mephenesin[J]. Journal of the American Chemical Society, 1952, 74 (8) : 1935-1939.|[5]DIAZ-RIVERA RS, et al. Muscular relaxation in tetanus with special reference to the effect of mephenesin. Ann Intern Med. 1954 Mar;40 (3) :563-80.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
NMDA Receptor
Available Sizes
Frequently Asked Questions
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