Neurokinin Receptor (393-407), rat
Neurokinin Receptor (393-407), rat (SPR393–407) is a rat neurokinin 1 receptor (NK1R) fragment. NK1R is rapidly internalized by endocytosis and recycled to the plasma membrane when binding to substance P (SP) . Neurokinin Receptor (393-407), rat can be used in the research of neurogenic inflammation[1][2].
Product Specifications
CAS Number
153607-26-2
Product Name Alternative
SPR393-407
UNSPSC
12352209
Target
Neurokinin Receptor
Type
Peptides
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/neurokinin-receptor-393-407-rat.html
Solubility
10 mM in DMSO
Smiles
OC(C=C1)=CC=C1C[C@@H](C(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCSC)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)NC([C@@H](NC([C@H](CO)NC([C@H](CO)NC([C@H](CO)NC([C@H](CCC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCSC)NC([C@H]([C@H](O)C)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)=O)=O)CC2=CC=CC=C2)=O
Molecular Formula
C72H113N17O26S2
Molecular Weight
1696.90
References & Citations
[1]Nathan JD, et al. Capsaicin vanilloid receptor-1 mediates substance P release in experimental pancreatitis. Am J Physiol Gastrointest Liver Physiol. 2001 Nov;281 (5) :G1322-8. |[2]Vigna SR, et al. Characterization of antibodies to the rat substance P (NK-1) receptor and to a chimeric substance P receptor expressed in mammalian cells. J Neurosci. 1994 Feb;14 (2) :834-45.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NK1R
Frequently Asked Questions
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