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IL-6 (Mouse) (MP5-20F3), 0.2mg/mL

IL-6 is a potent lymphoid cell growth factor that stimulates the growth and survivability of certain B-cells and T-cells. IL-6 plays a role in host defense, acute phase reactions, immune responses, and hematopoiesis. IL-6 is expressed by T-cells, B-cells, monocytes, fibroblasts, hepatocytes, endothelial cells and keratinocytes.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Product Specifications

CAS Number

9007-83-4

Synonyms

B cell differentiation factor; B-cell stimulatory factor 2 (BSF-2) ; CTL differentiation factor (CDF) ; Cytotoxic T cell differentiation factor; Hepatocyte stimulating factor; HPGF; HSF; Hybridoma growth factor Interferon beta-2; Hybridoma plasmacytoma growth factor; Interferon beta-2 (IFNB2)

UNSPSC

41116161

UNSPSC Description

Primary and secondary antibodies for multiple methodology immunostaining detection application

Gene ID

16193 (Mouse)

NCBI Gene ID

1019 (Mouse)

UniProt

P08505 (Mouse)

Swiss Prot

P08505 (Mouse)

Host

Rat

Species Reactivity

Mouse

Reactivity

IL-6

Immunogen

Recombinant mouse IL-6 protein

Target Antigen

IL-6

Clonality

Monoclonal

Clone

MP5-20F3

Type

Primary

Source

Animal

Origin

Animal

Applications

Flow, intracellular (published) |Functional studies (published)

Field of Research

Cytokines, Immunology, Inflammation

Positive Control

Mouse heart

Stability

2 years

Concentration

0.2 mg/mL

Buffer

PBS, 0.05% BSA, 0.05% azide

Molecular Weight

21 kDa

References & Citations

Note: References for this clone sold by other suppliers may be listed for expected applications. J Immunol (1990) 145(12): 4185-4191. (functional studies) J Immunol (2013) 190:703-711. (functional studies; Flow)

Shipping Conditions

RT (ND)

Storage Conditions

Stable at room temperature or 37°C (98°F) for 7 days.

Shelf Life

Guaranteed for at least 24 months from date of receipt when stored as recommended

Fragment

IgG1, kappa

Species

Rattus norvegicus (laboratory rat), BSA from bovine serum (Bos taurus) or recombinant BSA produced in Chinese hamster ovary cells.

Classification

PBS, 0.05% BSA, 0.05% sodium azide (CAS 26628-22-8)

Conjugate

Purified, with BSA

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