Anti-IgM Immunoglobulin(IM260)
Recognizes a protein of 75 kDa, identified as mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. This MAb is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant._x000D_ _x000D_ Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors._x000D_ _x000D_
Product Specifications
Synonyms
AGM1; IGHM; Constant Region of Heavy Chain of IgM; Ig Mu Chain C Region
UNSPSC
41116161
UNSPSC Description
Primary and secondary antibodies for multiple methodology immunostaining detection application
Gene Name
IGHM
Gene ID
3507
NCBI Gene ID
510635
UniProt
P01871; P20769
Cellular Locus
Plasma membrane|Secreted (extracellular)
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant heavy chain of human IgM
Target Antigen
Human IgM
Clonality
Monoclonal
Isotype
IgG1 κ
Clone
IM260
Conjugation
Purified, BSA-free
Disease
Tumor
Source
Animal
Applications
IHC, FFPE (verified) | WB (verified)
Validated Applications
IHC,FFPE,WB
Field of Research
Cancer, Immunology, Inflammation
Positive Control
293T, Raji or hPBL cells. Tonsil or Spleen
Concentration
1 mg/mL
Buffer
PBS, no BSA, no azide
Molecular Weight
50-75 kDa
Additionnal Information
Shipping Conditions
Room temperature
Storage Conditions
-35°C to -5°C ; Stable at room temperature or 37°C (98°F) for 7 days.
Shelf Life
2 years
Product Datasheet
https://cdn.gentaur.com/products/37/883465/datasheet/bnum0260-50.pdf
Product MSDS
https://cdn.gentaur.com/products/37/883465/msds/bnum0260-50.pdf
CAS Number
9007-83-4
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