QPRT Mouse Monoclonal Antibody [Clone ID: LBI4E5]

Product Specifications

Background

This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. [provided by RefSeq]. COMPLETENESS: complete on the 3' end.

Overview

Anti-QPRT mouse monoclonal antibody, clone LBI4E5

Synonyms

HEL-S-90n; QPRTase

Gene Name

Quinolinate phosphoribosyltransferase

Gene ID

23475

UniProt

Q15274

Conjugation

Unconjugated

Related Pathways

Metabolic pathways, Nicotinate and nicotinamide metabolism

Field of Research

Metabolic pathways, Nicotinate and nicotinamide metabolism

Concentration

0.63 mg/ml

Dilution

WB 1:500~2000, IF 1:100, FLOW 1:100

Form

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Buffer

PBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.