MIND4
MIND4 is a neuroprotective thiozoline compound that inhibits the deacetylase SIRT2. MIND4 is also an inducer and activator of the nuclear factor NRF2. MIND4 can induce NRF2 activation in neurons and non-neuronal cells and reduce the production of reactive oxygen and nitrogen intermediates[1].
Product Specifications
CAS Number
1639965-26-6
UNSPSC
12352005
Target
Drug Intermediate
Type
Reference compound
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/mind4.html
Smiles
O=[N+]([O-])C1=C2C=CC=NC2=C(C=C1)SC3=NN=C(N3C4=CC=CC=C4)COC5=CC=CC=C5
Molecular Formula
C24H17N5O3S
Molecular Weight
455.49
References & Citations
[1]SIRT2- and NRF2-Targeting Thiazole-Containing Compound with Therapeutic Activity in Huntington’s Disease Models
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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