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Alkaline phosphatase, microorganism

Alkaline Phosphatase (Apase), microorganism is an alkaline phosphatase from microorganism, and is one of the most active alkaline phosphatases. Alkaline phosphatase, microorganism is an orally active membrane-bound glycoprotein that catalyzes the hydrolysis of phosphate monoesters at alkaline pH. Alkaline phosphatase, microorganism reduces myeloperoxidase activity and bacterial translocation. Alkaline phosphatase, microorganism improves survival rate of mice infected with E. coli. Alkaline phosphatase, microorganism improves TNBS-induced colon inflammation[1][2][3][4][5][6].

Product Specifications

CAS Number

9001-78-9

Product Name Alternative

Apase, microorganism

UNSPSC

12352204

Target

Bacterial; Endogenous Metabolite; Glutathione Peroxidase; Phosphatase

Type

Enzyme

Related Pathways

Anti-infection; Apoptosis; Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/alkaline-phosphatase-microorganism.html

Smiles

[Alkalinephosphatase,microorganism]

References & Citations

[1]Beumer C, et al. Calf intestinal alkaline phosphatase, a novel therapeutic drug for lipopolysaccharide (LPS) -mediated diseases, attenuates LPS toxicity in mice and piglets. J Pharmacol Exp Ther. 2003 Nov;307 (2) :737-44.|[2]van Veen SQ, et al. Bovine intestinal alkaline phosphatase attenuates the inflammatory response in secondary peritonitis in mice. Infect Immun. 2005 Jul;73 (7) :4309-14.|[3]Hyoju SK, et al. Intestinal alkaline phosphatase decreases intraperitoneal adhesion formation. J Surg Res. 2017 Feb;208:84-92.|[4]Martínez-Moya P, et al. Exogenous alkaline phosphatase treatment complements endogenous enzyme protection in colonic inflammation and reduces bacterial translocation in rats. Pharmacol Res. 2012 Aug;66 (2) :144-53.|[5]Ujjawal Sharma, et al. Alkaline Phosphatase: An Overview. Indian J Clin Biochem. 2014 Jul; 29 (3) : 269-278.|[6]Chirambo GM, et al. The role of alkaline phosphatase in intracellular lipid accumulation in the human hepatocarcinoma cell line, HepG2. Exp Mol Pathol. 2017 Apr;102 (2) :224-229.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Frequently Asked Questions

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